Coleus forskohlii
An ancient Ayurvedic medicinal plant and source of forskolin, a compound shown to have modest effects on fat loss. Standardized extracts are often included in weight loss supplement formulas.
Forskolin
The active ingredient in Coleus forskohlii – an ancient Ayurvedic medicinal plant. Forskolin stimulates production of a cellular “messenger” – cAMP (cyclic AMP) – which, in turn, stimulates production of hormone sensitive lipase (HSL), an enzyme involved in the breakdown of stored fat. Forskolin (typically in the form of standardized extracts) is a common ingredient in fat loss supplements. Most of the studies published on forskolin have used cell cultures, although one peer-reviewed study shows (modest) effects in humans, as well.
L-Leucine
An essential amino acid and one of the “branched chain amino acids” (BCAAs). In addition to being a component of body proteins, leucine serves an important function as an initiator of muscle protein synthesis. Leucine and the other BCAAs (valine and isoleucine) are often taken in supplemental form by bodybuilders, to offset catabolism during workouts and promote post-workout recovery.
See the BCAA review for more information.
Trimethylglycine
See Betaine.
Betaine
Also known as trimethylglycine. A naturally-occurring nutrient/metabolite with therapeutic applications. Supplemental betaine can help reduce homocysteine (a risk factor for cardiovascular disease) and treat non-alcoholic fatty liver disease. Betaine HCl is also a source of hydrochloric acid, and can be used to compensate for decreased production by the stomach (hypochlorhydria).
See the University of Maryland Medical Center for more information.
Maltodextrin
A glucose polymer created from corn, rice or potato starch.
Maltodextrins are intermediate in size between starches and sugars/syrups. They’re flavorless, which makes them useful as food additives. Maltodextrins are used as bulking or dispersing agents, to modify viscosity or mouthfeel; and as a carrier for flavors in a variety of different food products.
Maltodextrin is often used as a carb source in meal replacements, weight gainers, and creatine delivery systems. “Malto” typically has a high glycemic index (similar to glucose), but is technically a “complex carbohydrate” – which enables manufacturers to claim that no sugar has been added to their products.
See “Making the Most of Maltodextrins” for more information.