The UFB Glossary - Glossary

The UFB Glossary

Ponasterone A

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See 25-Deoxy-20-Hydroxyecdysone.

25-Deoxy-20-Hydroxyecdysone

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Also known as Ponasterone A.  An ecdysteroid and analog of 20-hydroxyecdysone.  25-Deoxy-20-Hydroxyecdysone is sometimes listed as a component of standardized extracts used in bodybuilding supplements, although there is little information on what effects – if any – it has on mammals when given in isolation (FYI: one chemical supplier states it’s “inert to mammalian physiology”).

20-Beta-Hydroxyecdysone

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See 20-Hydroxyecdysone.

Beta-Ecdysone

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See 20-Hydroxyecdysone.

Hydroxyecdysone

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See 20-hydroxyecdysone.

20-Hydroxyecdysone

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An ecdysteroid shown to have modest, growth-promoting and muscle-building effects in animal experiments. 20-hydroxyecdysone (or plant extracts standardized for 20-hydroxyecdysone) is non-toxic, and used in a variety of bodybuilding supplements, but whether it actually helps increase muscle mass and strength in humans is unknown.  A small, 2006 study on resistance-trained males taking a standardized, Polypodium vulgare/Suma root extract showed no effect at the dose administered.

Supplements containing 20-hydroxyecdysone (CAS 5289-74-7) use a variety of synonyms, including 20-beta-hydroxyecdysterone, beta-ecdysterone, beta-ecdysone, 20-hydroxy-ecdysterone, 20-beta-hydroxy ecdysone,  hydroxyecdysone, ecdysterone, and ecdisten.