Guanidinopropionic Acid
A creatine analog. GPA has been shown to increase insulin sensitivity and glucose clearance in animal experiments. It’s often added to creatine transport formulas for this reason…despite the fact that it also inhibits creatine uptake and – in higher amounts – depletes creatine phosphate in muscle cells (which is why other GPA analogs have been investigated as anti-diabetic/anti-obesity agents).
